The 5 Best Niacinamide Serums You Need to Know About

Looking for the best niacinamide serums? This list includes 5 of the top-rated serums on Amazon, all with niacinamide as a key ingredient.

The 5 Best Niacinamide Serums You Need to Know About
Niacinamide Serum for Face
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Niacinamide, also known as nicotinamide, is having a moment in the beauty world. This appearance-boosting ingredient is found in a variety of skincare products, from serums and creams to shampoos and toners. But what exactly is niacinamide, and what does it do for your skin? Let's take a closer look.

Niacinamide is a form of vitamin B3. topically applied, niacinamide can help improve the appearance of various skin concerns, such as fine lines and wrinkles, dullness, and uneven skin tone. Niacinamide can also help to reduce the redness associated with certain skin conditions, like acne and rosacea. In addition, niacinamide is an effective antioxidant that can help protect the skin from environmental stressors, such as pollution and UV rays.

For the purposes of this blog post, we will focus on niacinamide serums as they are the most potent form of this wonder ingredient.

When applied topically, niacinamide increases ceramide production which strengthens the skin barrier and helps to lock in moisture. In addition, niacinamide decreases inflammation and redness while also helping to lighten pigmentation (age spots, sun spots, etc.). For these reasons, niacinamide is an excellent choice for those with dry or sensitive skin as well as those concerned with aging skin.

Now that we know all about niacinamide and why it's so great for our skin, let's talk about some of the best niacinamide serums on the market today.

Pick Number 1

DOUBLE SIZED (2Oz) Niacinamide Serum by InstaSkinCare

DOUBLE SIZED Niacinamide Serum by InstaSkinCare

Why Do We Like it?

+23,500 ratings
4.4 out of 5.0 stars
7% 1 & 2 stars

Ingredients: Niacinamide, Hyaluronic Acid, Zinc & Coconut Extract gently affects your skin, intensively improving it. Their vitamin B3 serum is non-irritative & perfect even for the most sensitive skin.

Double-Sized Niacinamide Serum by InstaSkinCare is a powerful serum that is perfect for those who want to achieve healthier skin. Formulated with organic ingredients, the Niacinamide Serum effectively reduces acne and heals post-acne scars. It also regulates skin tone, decreases oiliness, and fades post-acne marks, making your skin more even overall. With regular use, you'll notice a noticeable difference in your skin's appearance within 14 days. The Bye Hyperpigmentation serum is also great for fighting pigmentation, dark circles, and discoloration.

Pick Number 2

Advanced Clinicals Niacinamide Serum - 5% Niacinamide Serum for Face with Hyaluronic Acid Serum

Advanced Clinicals Niacinamide Serum

Why Do We Like it?

+17,600 ratings
4.5 out of 5.0 stars
7% 1 & 2 stars

Introducing our new Advanced Clinicals Niacinamide Serum - 5% Niacinamide Serum for Face with Hyaluronic Acid. This niacinamide serum is specifically formulated with hyaluronic acid and ferulic acid to be gentle, effective, and safe for all skin types. The concentration of niacinamide in Advanced Clinicals serum is 5%, which is the optimum level for maximum effectiveness without causing skin irritation.

This niacinamide serum helps to brighten and clarify the skin, while also reducing the appearance of fine lines and wrinkles. The zinc and magnesium in our serum help to slow down the signs of aging, leaving you with a satin-smooth, hydrated finish that looks plumped from within.

Pick Number 3

Tree of Life Refining Niacinamide Serum

Tree of Life Refining Niacinamide Serum

Why Do We Like it?

+5,300 ratings
4.5 out of 5.0 stars
6% 1 & 2 stars

If you're looking for an all-in-one serum to brighten and even out your complexion, Tree of Life's Refining Niacinamide Serum is the perfect solution. Niacinamide (aka Vitamin B3) is clinically proven to reduce the appearance of pores and even out skin tone, while hyaluronic acid locks in moisture for a plump and smooth look.

Certified organic aloe vera provides additional hydration, making this serum ideal for those with dry or sensitive skin. Plus, it's certified cruelty-free and vegan, with no parabens, so you can feel good about using it every day. Add it to your morning and evening routine after cleansing and before applying face cream, or alternate with a topical Vitamin C cream if you're using one. You'll love the results!

Pick Number 4

The New Ordinary Niacinamide by Ombrace

The New Ordinary Niacinamide by Ombrace

Why Do We Like it?

+184 ratings
4.6 out of 5.0 stars
2% 1 & 2 stars

The New Ordinary by Ombrace is a unique formula that contains 10% niacinamide and 1% zinc, making it ideal for those with oily or acne-prone skin. Niacinamide is a form of vitamin B3 that helps to control oil production and reduce inflammation, while zinc helps to regulate sebum production and soothe the skin. Together, these ingredients create a powerhouse serum that will help to keep your skin looking its best.

The New Ordinary Niacinamide Serum comes in a handy 30ml (1oz) bottle with a pump dispenser, making it easy to apply to your face and neck. Simply apply a few drops of the serum to clean skin once or twice daily, and follow with your favorite moisturizer. You'll soon see a visible difference in your skin's appearance, with fewer breakouts and a more even complexion.

Pick Number 5

Niacinamide Serum Essence by DEBAI

Niacinamide Serum Essence by DEBAI

Why Do We Like it?

+350 ratings
4.4 out of 5.0 stars
6% 1 & 2 stars

Introducing the Niacinamide Serum Essence by DEBAI – a natural and effective way to achieve brighter, more youthful skin. Formulated with 5% niacinamide and a blend of other powerful ingredients like hyaluronic acid, vitamin E, vitamin C, and zinc, this serum essence works to inhibit melanin production, accelerate skin repair, lighten dark spots, and brighten skin tone. It's also an excellent anti-aging treatment that shrinks pores and reduces the appearance of wrinkles. Safe for women, men, and teens to use, this serum essence is perfect for anyone who wants to achieve healthier, more radiant skin.

Summing Up

Ready to give niacinamide a try? Excellent! Just remember to always do a patch test on a small area of skin before applying any new product all over your face. And if you're looking for a good place to start your search for the perfect niacinamide serum, check out our list of five favorites above.

FAQ About Niacinamide Serum

We have compiled the most frequently asked questions about niacinamide serum so you can get all the information you need before making a purchase.

Can I use niacinamide serum every day?

Yes, you can use niacinamide serum every day. In fact, we recommend using it twice a day for the best results.

Can I use niacinamide serum with other products?

Yes, you can use niacinamide serum with other products. Just remember to always do a patch test on a small area of skin before applying any new product all over your face.

Do I need to use a separate niacinamide serum and moisturizer?

No, you don't need to use a separate niacinamide serum and moisturizer. Just apply the serum to your face and neck after cleansing, and follow with your favorite moisturizer.

Is niacinamide serum safe for pregnant women?

Yes, niacinamide serum is safe for pregnant women. However, we recommend that you always consult with your healthcare provider before using any new product during pregnancy.

What are the side effects of niacinamide serum?

There are no known side effects of niacinamide serum. However, as with any new product, we recommend that you always do a patch test on a small area of skin before applying it all over your face.

Do I need to use sunscreen while using niacinamide serum?

Yes, you should always use sunscreen while using niacinamide serum. Niacinamide can make your skin more sensitive to the sun, so it's important to protect your skin from harmful UV rays.

What is the best time of day to use niacinamide serum?

The best time of day to use niacinamide serum is in the morning after cleansing and before applying sunscreen and makeup. You can also use it at night after cleansing and before applying your favorite night cream.

How long does it take for niacinamide serum to work?

You should start to see results from using niacinamide serum within a few weeks. However, everyone's skin is different, so results may vary.

How do I apply niacinamide to my face?

To apply niacinamide to your face, start by cleansing your skin. Then, apply a small amount of serum to your face and neck. Gently massage it into your skin until it's fully absorbed. Finish by applying your favorite moisturizer.

Can I use niacinamide serum if I have sensitive skin?

Yes, you can use niacinamide serum if you have sensitive skin. Just remember to always do a patch test on a small area of skin before applying any new product all over your face.

Who should not use niacinamide serum?

People who have very sensitive skin, or those with rosacea, should avoid using niacinamide serum. It is also not recommended for pregnant women or those who are breastfeeding. If you're not sure whether niacinamide is right for you, it's best to consult a dermatologist before starting any new skincare routine.

Does niacinamide work immediately?

No, it doesn't work immediately. In fact, it can take a few weeks for you to start seeing the full benefits of niacinamide. That being said, some people do start to see results sooner than that. It just depends on the individual.

How long should I leave niacinamide on my face?

You don't need to rinse off the niacinamide serum. Just apply it to your face and neck after cleansing, and massage it into your skin until it's fully absorbed. Then, you can apply your favorite moisturizer.

Which is better vitamin C or niacinamide?

Vitamin C is better.  Niacinamide, while a form of vitamin B3, does not have the same effects as vitamin C. Niacinamide can actually work to decrease the effectiveness of vitamin C. So, if you're looking for the benefits that vitamin C provides - such as antioxidant and anti-inflammatory properties - then it's best to stick with pure vitamin C supplements.

Does niacinamide lighten skin?

Yes, niacinamide can lighten skin. It does so by inhibiting melanin synthesis.

Melanin is the pigment that gives skin its color. When too much melanin is produced, it can cause patches of darker skin (e.g., freckles, age spots, and melasma). Niacinamide reduces melanin production by blocking the enzyme tyrosine oxidase, which is needed to produce melanin. This makes niacinamide a potential treatment for hyperpigmentation disorders.


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